GIT diseases
Crohn
disease
diffuse labial,
gingival or mucosal swelling
cobblestoning of buccal mucosa
and gingiva
aphtous ulcers
mucosal tags
angular cheilitis
oral granulomas
 |
Crohn
disease
|
Ulcerative
colitis
oral signs are
present in periods of exacerbation of disease
aphtous
ulceration or superficial hemorrhagic ulcers
angular
stomatitis
pyostomatitis
vegetans, pyostomatitis gangrenosum
 |
| pyostomatitis vegetans |
Gastroesophageal
reflux
reduction of the
pH of the oral cavity below 5,5 – enamel damage
damage of the
dentin – higher sensitivity (to temperature..), caries
 |
enamel damage and
damage of the dentin
|
Chronic
liver diseases
jaundice
petechiae or
gingival bleeding (hemostasis disorder)
Hematologic diseases
Anemias
folate and vit.
B12 deficiency or iron
deficiency
glossitis
red colour
atrophic papilae
recurrent aphthae
candidal infection
angular stomatitis
oral pain
Leukemia
gingival hypertrophy
petechiae
mucosal ulcers
hemorrhage
Treatment of leukemia
reactivation of herpes simplex virus – oral mucosistis
 |
| gingival hypertrophy in leukemia |
|
Summary of oral manifestations
of gastrointestinal and
hematologic diseases
|
|
|
Labial
swelling
Crohn's disease
|
Glossitis
Crohn's disease
Iron-deficiency anemia
Pernicious anemia
Ulcerative colitis
|
|
Erosion
of enamel and dentin
Anorexia nervosa/bulimia
Gastroesophageal reflux
|
Ulcerations
and erosions
Crohn's disease
Iron-deficiency anemia
Pernicious anemia
Pyostomatitis vegetans
Ulcerative colitis
|
|
Gingivitis
Anorexia nervosa/bullimia
Crohn's disease
Scurvy
|
Hemorrhage
Pyostomatitis vegetans
Scurvy
Ulcerative colitis
|
|
Angular
cheilitis
Iron-deficiency anemia
|
Aphthous
ulcers
Crohn's disease
Pernicious anemia
Ulcerative colitis
|
|
Intraoral
burning
Iron-deficiency anemia
Pernicious anemia
|
Candidiasis
Crohn's disease (steriod therapy)
Iron-deficiency anemia
Pyostomatitis vegetans (steriod therapy)
Ulcerative colitis (steroid therapy
|
Connective-tissue diseases
Sjรถgren syndrome
autoimmune disease
men : women - 1 : 9
50 years and older
Main signs
sicca syndrome
keratoconjuctivitis sicca
xerostomia
Oral signs
decrease in saliva
xerostomia
dry, red, wrinkled mucosa
difficulty in swalloving and eating
disturbance in taste and speech
increased dental caries
infections
atrophy of the papilae
candidiasis
Kawasaki
disease
vasculitis of medium and large arteries
Oral signs
swelling of papilae on the surface of the tongue (strawbery tongue)
intense erythema of the mucosal surfaces
cracked, cherry red, swolen and hemorrhagic lips
Scleroderma
diffuse sclerosis of the skin, GIT, heart muscle, lungs, kidney
Oral signs
pursed lips – dificult to open the mouth
esophageal sclerosis ® gastroesophageal reflux – damage of enamel
pale, rigid mucosa
teleangiectasias
decreased mobility of tongue
salivary hypofunction
Lupus
erythematosus
autoimmune disease
Oral signs
ulcerations
similar tooral lesions of lichen planus – painful
petechiae
damage of salivary glands - xerostomia
Pulmonary diseases
Cystic
fibrosis
Oral signs
disorder of salivary glands
swelling lips
gingivitis
dryness
Sarcoidosis
Oral signs
multiple, nodular, painles ulcerations of the gingiva, bucal mucosa, labial
mucosa and palate
tumorlike swelling of salivary glans
swelling of the tongue
xerostomia
facial nerve palsy
Cutaneous
diseases
Psoriasis
Oral signs
fissured tongue
small white papules
red and white plagues
bright red patches
Acantosis
nigricans
hyperpigmentation, papillomatosis
Oral signs
gingival hyperplasia
gingiva, tongue, lips – papilomas
Endocrine diseases
Diabetes
mellitus
Oral signs
xerostomia caused decreased salivation and increased glucosa level in
saliva
gingivitis
oral infections
candidiasis
higher incidence of caries
bilateral enlargement of parotid glands
altered taste
burning mouth syndrome
Hypoparathyroidism
Oral signs
candidiasis
upper lip twitching
Hyperparathyroidism
Oral signs
loss of the lamina dura surrounding the roots of the teeth
decrease of trabecular density
osseous lesions „brown tumor“
Cushing´s
syndrome
Oral signs
fatty tissue deposition – „moon face“
osteoporosis ® pathological
fractures of the mandible, maxilla or alveolar bone
delayed healing of fractures and also sof tissue injuries
 |
| moon face |
Addison´s
disease
Oral signs
„bronzing“ hyperpigmentation of the skin
oral mucosal melanosis – buccal mucosa, tongue
 |
| hyperpigmentation |
Renal diseases
Uremic
stomatitis
rare
in undiagnosed and untreated chronic renal failure
irritation and chemical injury of mucosa by ammonia or ammonium compounds
Signs
painful plagues and crusts – bucal mucosa, the floor or dosrum of the
tongue, floor of the mouth
Type I
generalized or localized erythema
exudate
pain, burning, xerostomia, halitosis, gingival bleeding, candidiosis
Type II
ulceration
secondary infection
anemia
 |
| painful plagues and crusts – bucal mucosa, the floor or dosrum of the tongue, floor of the mouth |
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