Wednesday, August 3, 2011

A Note On Primary Herpes Simplex Virus Infections.......Extracted from Burket’s Oral Medicine

There are approximately 600,000 new cases of primary HSV infections per year in the United States. Primary HSV infection occurs in patients who do not have immunity resulting from previous contact with the virus. HSV is contracted after intimate contact with an individual who has active HSV primary or recurrent lesions. Primary HSV may also be spread by asymptomatic shedders with HSV present in salivary secretions. The majority of oral HSV infections is caused by HSV1, but primary oral HSV2 infections may also occur chiefly as a result of oral-genital contact. Infection of the fingers (herpetic whitlows) of health professionals may occur during treatment of infected patients. Dentists may experience primary lesions of the fingers from contact with lesions of the mouth or saliva of patients who are asymptomatic carriers of HSV, although the incidence of this disorder should be minimal if gloves are worn. Use of gloves should also prevent the spread of HSV from the fingers of health care workers infected with herpetic whitlows to patients.





Primary herpetic whitlow on the finger of a dentist








Primary HSV infection of the newborn was previously believed to be caused by direct contact with vaginal HSV lesions during birth, but it has now been established that a majority of mothers giving birth to children with primary HSV are asymptomatic carriers without lesions. These infections of the newborn result in viremia and disseminated infection of the brain, liver, adrenals, and lungs.
Newborns of mothers with antibody titers are protected by placentally transferred antibodies during the first 6 months of life. After 6 months of age, the incidence of primary HSV1 infection increases. The incidence of primary HSV1 infection reaches a peak between 2 and 3 years of age. Incidence of primary HSV2 infection does not increase until the age when sexual activity begins. Studies of neutralizing and complement-fixing antibodies to HSV have shown a continual rise in the percentage of patients who have had contact with the virus until 60 years of age, demonstrating that although the primary infection with HSV1 is chiefly a disease of infants and children, new cases continue to appear during adult life. This is consistent with the many reports of adults with primary herpetic gingivostomatitis.
The incidence of primary herpes infection has been shown to vary according to socioeconomic group. In lower socioeconomic groups, 70 to 80% of the population have detectable antibodies to HSV by the second decade of life, indicating prior HSV infection, whereas, in a group of middle class individuals, only 20 to 40% of the patients in the same age group have evidence of contact with HSV.
A significant percentage of cases of primary herpes are subclinical, although the apparently low incidence of a history of classic primary herpetic gingivostomatitis is also influenced by the young age of patients who develop the infection, by the improper diagnosis of some cases, and by the cases of primary herpetic pharyngitis that cannot be clinically distinguished from other causes of viral pharyngitis.

CLINICAL MANIFESTATIONS OF PRIMARY ORAL HERPES
The patient usually presents to the clinician with full-blown oral and systemic disease, but a history of the mode of onset is helpful in differentiating lesions of primary HSV infection from other acute multiple lesions of the oral mucosa. The incubation period is most commonly 5 to 7 days but may range from 2 to 12 days. Patients with primary oral herpes have a history of generalized prodromal symptoms that precede the local lesions by 1 or 2 days. This information is helpful in differentiating this viral infection from allergic stomatitis or erythema multiforme, in which local lesions and systemic symptoms appear together. These generalized symptoms include fever, headache, malaise, nausea, and vomiting. A negative past history of recurrent herpes labialis and a positive history of direct intimate contact with a patient with primary or recurrent herpes are also helpful in making the diagnosis.
Approximately 1 or 2 days after the prodromal symptoms occur, small vesicles appear on the oral mucosa; these are thin-walled vesicles surrounded by an inflammatory base. The vesicles quickly rupture, leaving shallow round discrete ulcers. The lesions occur on all portions of the mucosa. As the disease progresses, several lesions may coalesce, forming larger irregular lesions.


A 12-year-old female with primary herpetic gingivostomatis causing discrete vesicles and ulcers surrounded by inflammation





An  important diagnostic criterion in this disease is the appearance of generalized acute marginal gingivitis. The entire gingiva is edematous and inflamed. Several small gingival ulcers are often present. Examination of the posterior pharynx reveals inflammation, and the submandibular and cervical lymph nodes are characteristically enlarged and tender. On occasion, primary HSV may cause lesions of the labial and facial skin without intra-oral lesions.
      Acute marginal gingivitis characteristic of primary HSV infection. A, mandibular anterior gingiva; B,  vesicles and inflammation around mandibular molars

Primary HSV in otherwise healthy children is a self-limiting disease. The fever ordinarily disappears within 3 or 4 days, and the lesions begin healing in a week to 10 days, although HSV may continue to be present in the saliva for up to a month after the onset of disease.

LABORATORY DIAGNOSIS
The diagnosis of primary herpetic gingivostomatitis is straight-forward when patients present with a typical clinical picture of generalized symptoms followed by an eruption of oral vesicles, round shallow symmetric oral ulcers, and acute marginal gingivitis. Laboratory tests are rarely required in these cases. Other patients, especially adults, may have a less typical clinical picture, making the diagnosis more difficult. This is especially important when distinguishing primary herpes from erythema multiforme since proper therapy differs significantly.
The following laboratory tests are helpful in the diagnosis of a primary herpes infection.
Cytology
 For cytology, a fresh vesicle can be opened and a scraping made from the base of the lesion and placed on a microscope slide. The slide may be stained with Giemsa, Wright’s, or Papanicolaou’s stain and searched for multinucleated giant cells, syncytium, and ballooning  degeneration of the nucleus. Fluorescent staining of cytology smears has been shown to be more sensitive (83%) compared with routine cytology (54%); it is the cytologic test of choice, when available.
                  Cytology smear stained with Giemsa, demonstrating multinucleated giant cells
HSV Isolation
Isolation and neutralization of a virus in tissue culture is the most positive method of identification and has a specificity and sensitivity of 100%. A clinician must remember that isolation of HSV from oral lesions does not necessarily mean that HSV caused the lesions. Patients who have lesions from other causes may also be asymptomatic shedders of HSV.
Antibody Titers
Conclusive evidence of a primary HSV infection includes testing for complement-fixing or neutralizing antibody in acute and convalescent sera. However, it is rarely necessary in routine clinical situations and is often not helpful since the results are not available until the infection is gone. In special circumstances, such as immunocompromised patients, an acute serum specimen should be obtained within 3 or 4 days of the onset of symptoms. The absence of detectable antibodies plus the isolation of HSV from lesions is compatible with the presence of a primary HSV infection. Antibody to HSV will begin to appear in a week and reach a peak in 3 weeks. A convalescent serum can confirm the diagnosis of primary HSV infection by demonstrating at least a fourfold rise in anti-HSV antibody. If anti-HSV antibody titers are similar in both the acute and convalescent sera, then the lesions from which HSV was isolated were recurrent lesions.

TREATMENT
A significant advance in the management of herpes simplex infections was the discovery of acyclovir, which has no effect on normal cells but inhibits DNA replication in HSV-infected cells.  Acyclovir has been shown to be effective in the treatment of primary oral HSV in children when therapy was started in the first 72 hours. Acyclovir significantly decreased days of fever, pain, lesions, and viral shedding. Newer anti-herpes drugs are now available, including valacyclovir and famciclovir. The advantage of the newer drugs is increased bioavailability, allowing for effective treatment with fewer doses. Milder cases can be managed with supportive care only.
Routine supportive measures include aspirin or acetaminophen for fever and fluids to maintain proper hydration and electrolyte balance. If the patient has difficulty eating and drinking, a topical anesthetic may be administered prior to meals. Dyclonine hydrochloride 0.5% has been shown to be an excellent topical anesthetic for the oral mucosa. If this medication is not available, a solution of diphenhydramine hydrochloride 5 mg/mL mixed with an equal amount of milk of magnesia also has satisfactory topical anesthetic properties. Infants who are not drinking because of severe oral pain should be referred to a pediatrician for maintenance of proper fluid and electrolyte balance.
Antibiotics are of no help in the treatment of primary herpes infection, and use of corticosteroids is contraindicated. Future therapy may include prevention of the infection with use of a genetically disabled HSV vaccine.

31 comments:

  1. Am Joyce Benson, I want to testify about how Dr.Ekpiku help me to cure my herpes virus. It was in my brain causing constant pounding and messing with my sight. It tingles at the base of my spine all the time and messes hugely with my bowel function. My right leg was numb and I can not sleep at night because of the symptoms. This was hell on earth. I have tried everything to get off the virus but nothing comes out good on it. I saw so many testimony on how Dr. Ekpiku the herbs medicine man help to cure so many people herpes. So i contact him for help and tell him my herpes problem. He assure me that i will be negative after he finish casting the spell for 48 hours. He cast the spell and asked me to go for check-up after three days of casting the spell, Luckily for me were tested herpes negative, now I believe all these Testimonies about him on the internet, he is truly a great man, I am now free from herpes all thanks goes to Dr. Ekpiku for what he did in my life...If you are out there have herpes problem or any other disease you have to seek for his help because he is going to help you cure your herpes or any other sickness. email him on: Ekpikuspellhomeofgrace@gmail.com or Ekpikuspellhomeofgrace@hotmail.com or call him +2347055029151) THESE ARE THE THINGS Dr. Ekpiku. . HERPES . HIV/AIDS . CANCER...

    ReplyDelete
    Replies
    1. I’m here to testify about what Dr Okosun did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 4 years and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of Rose Smith on the internet testifying about a Man called Dr Okosun on how he cured her from 7 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,, Dr Okosun prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as Dr Okosun assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HBV, HIV, ALS, HBP, CANCER etc. you can contact Dr.Okosun for help via drokosun55@gmail or whatsapp +2348124363791

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  2. I am bold enough among many others to state that there is now a potent cure to this sickness but many are unaware of it. I discovered that I was infected with the virus 3 months ago, after a medical check-up. My doctor told me and I was shocked, confused and felt like my world has crumbled. I was dying slowly due to the announcement of my medical practitioner but he assured me that I could leave a normal life if I took my medications (as there was no medically known cure to Herpes). I went from churches to churches but soon found that my case needed urgent attention as I was growing lean due to fear of dying anytime soon. In a bid to look for a lasting solution to my predicament, I sought for solutions from the herbal world. I went online and searched for every powerful trado-medical practitioner that I could severe, cos I heard that the African Herbs had a cure to the Herpes syndrome. It was after a little time searching the web that I came across one Dr Itua(A powerful African Herbal Doctor), who offered to help me at a monetary fee. I had to comply as this was my final bus-stop to receiving a perfect healing. My last resolve was to take my life by myself, should this plan fail. At last it worked out well. He gave me some steps to follow and I meticulously carried out all his instructions. Last month, to be precise, I went back to the hospital to conduct another test and to my amazement, the results showed that negative,, You can free yourself of this Herpes virus by consulting this great African Herbal Doctor via this e-mail: drituaherbalcenter@gmail.com or call and whatsapp him on +2348149277967 He will help you and his herb medication is sure. he has the cure on all disease .

    ReplyDelete
  3. My name is Emilia Peters, I am here to give my testimony about a doctor who helped me in my life. I was infected with HERPES SIMPLEX VIRUS in 2017, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution out so that my body can be okay. One day I was in the river side thinking where I can go to get solution. so a lady walked to me telling me why am I so sad and i open up all to her telling her my problem, she told me that she can help me out, she introduce me to a doctor who uses herbal medication to cure HERPES SIMPLEX VIRUS and gave me his email, so i mail him. He told me all the things I need to do and also give me instructions to take, which I followed properly. Before I knew what is happening after two weeks the HERPES SIMPLEX VIRUS that was in my body got vanished . so if you are also heart broken and also need a help, you can also email him at:drejiehiwaseharbalcenter@gmail.com or call him or talk with him through wasap on +2347067607558
    You can also contact him if are diagnosed with any the virus below
    {1}HIV and AIDS
    {2}Diabetes
    {3}Epilepsy
    {4} Blood Cancer
    {5} He Can Make you get Pregnancy
    {6.} HPV
    {7} ALS
    {8} Hepatitis
    {9} Diabetes
    {10}Love Spell

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  4. I am glad with the invention of natural herbal permanent cure for herpes. Sometimes last year i was checking for permanent solution to this offensive infection i don't even know how i got, i came across so many testimonies shared about this herbal doctor called DR EMUA, I contented him and asked him for proves, just to be sure i was not in the wrong hands, he gave me so many proves and i had no option that to give him a try, just to cut everything short, i got a parcel from him through FedEx and he told me how to apply it which i did, after one month i went to the same doctor for a retest, and the doctor could not find any trace of herpes in my body, am so happy now, don't even know how to show the joy in me, if you have same sickness or any illness given you hard time i will advice you to contact this great healer called DR EMUA, You can contact him Via this email dremuahelphome@outlook.com or dremuahelphome@gmail.com for easy and fast communication you can also call or add him on whats-app with this number +2347063628174

    ReplyDelete
  5. I'm short of words to express the goodness of God in my life. I was diagnosed of herpes simplex virus 4 years ago. Which was the worst time in my life,cos of my career and i'm just 28th. I became worried,distress,felt so rejected,dirty and pity. I started keeping in touch with many hospitals,tried many solutions,and consulted many medical practitioners to get ride of my HSV virus,none of the ativiral treatment could cure me .I started trying fruits and herbs, and with time became very interested in herbs for solutions,to get ride of my HSV. I thought my life was gonna end there, i became worried and couldn't sleep at night. That faithful Sunday morning, friend of mine crystal who visited me home came up with a good news with her HIV/ AIDS test result negative. I was shocked,but so happy to have seen that. I wouldn't believe if I haven't seen the result and that would have being my worst mistake in life. She told me it was the work of an herbalist in Africa,Dr.Abang. who prepared the HIV/AIDS cured and sent it to her husband through the DHL. I became very interest and went online to search for natural ways for my cure then I saw a testimony of a lady comments on how she was cured from cancer by the same herbalist, then,I quickly email him@
    Odeyabangherbalhome@gmail.com.its med.are very active with immune booster with no site effect.contact him for the solution to all your sickness. He cures all viruses and diseases
    Odeyabangherbalhome@gmail.com
    Is a God sent in my life....

    ReplyDelete
  6. TESTIMONY OF HOW I GOT CURED FROM HERPES SIMPLEX VIRUS
    This is real take it serious, who will believe that herb can cure herpes, i never believe that this will work, i have spent a lot getting drugs from the hospital to keep me healthy, it got to a point that all i was waiting for is death to come because i was broke, one day i heard about this great man called Dr Lucky who is well know for Herpes, HIV, and Cancer cure, i decided to contact him, I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and sent it through Courier Service for delivery, he gave my details to the Courier Office, they told me that 3-5 days I will receive the package and after receiving it, i took the medicine as prescribed by him, after finishing the medicine, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, i thought it was a joke, i went to other hospital and was also negative, thank you for saving my life, I promise I will always testify of your good works. if you are herpes simplex virus patient, contact him and I am sure you will get cured too, contact him via
    Email: Email: tremendousherbalhome@gmail.com text: 559-332-6084

    ReplyDelete
  7. I have been suffering from (HERPES) disease for the last four years and had constant pain, especially in my knees. During the first year, I had faith in God that I would be healed someday.This disease started to circulate all over my body and I have been taking treatment from my doctor, a few weeks ago I came on search on the internet if I could get any information concerning the prevention of this disease, on my search I saw a testimony of someone who has been healed from (Hepatitis B and Cancer) by this Man Dr. Silver and she also gave the email address of this man and advise we should contact him for any sickness that he would be of help, so I wrote to Dr. Silver telling him about my (HERPES Virus) he told me not to worry that I was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later I started experiencing changes all over me as the Dr. assured me that I have cured, after some time i went to my doctor to confirmed if I have been finally healed behold it was TRUE, So friends my advice is if you have such sickness or any other at all you can email Dr. Silver (drsilverhealingtemple@gmail.com) sir I am indeed grateful for the help I will forever recommend you to my friends!!! with your lovely Email Address ( drsilverhealingtemple@gmail.com

    ReplyDelete






  8. My life is back!!! After 8 years of marriage, my husband left me and left me with our three kids. I felt like my life was about to end, and was falling apart. I contacted you and after I explained you my problem. In just 24hours, my husband came back to us and show me and my kids much love and apologize for all the pain he have bring to the family. We solved our issues, and we are even happier than before DR ODUCK AYAMUD you are the best spell caster i really appreciate the love spell you casted for me to get the man back to my life i will keep sharing more testimonies to people about your good work Thank you once again DR ODUCK AYAMUD at: oduckayamud49@yahoo.com OR oduckayamud49@gmail.com .... YOU CAN USE ANY OF THE EMAILS TO CONTACT HIM incase you are in any problem you can contact this man for help he is always there in his temple to help you solve your problem Contact Email is: oduckayamud49@yahoo.com OR oduckayamud49@gmail.com .... YOU CAN USE ANY OF THE EMAILS TO CONTACT HIM. CONTACT HIM TODAY VIA THIS EMAIL ADDRESS: oduckayamud49@yahoo.com OR oduckayamud49@gmail.com .... YOU CAN USE ANY OF THE EMAILS TO CONTACT HIM AS HIS POWERS ARE SO STRONG AND VERY EFFECTIVE AND HAS NO BAD EFFECT INSTEAD IT HAVE A VERY GOOD RESULT AFTER CASTING THE SPELL.... YOU CAN ALSO CALL / ADD HIM UP ON WHATSAPP USING THIS MOBILE NUMBER:+2347059232579



    ReplyDelete




  9. HOW I GET MY HERPES CURED WITHIN 8 DAYS

    I want every herpes patient to please read my testimony, my name is FLORA RUFER am from California in USA, I contacted genital herpes from my ex boyfriend who never had any symptoms. I have had it for 4 months now., and it has affected my life. I have told my boyfriends who I trusted about it and I have never had a bad reaction, it has affected my new relationships with penny and people think herpes is really a minor skin irritation herpes has a long term effects on health. The stigma attached to this virus by ignorant people is ridiculous. Most people have herpes in one form or another. I would like to advise people on how I get rid of my herpes and I was reading a comment on the internet,and I saw a testimony posted by a woman from island that she get rid of her herpes with the help of doctorODUCK AYAMUD and so I was so happy when I saw that post, that his herbal medication is free and I quickly collected the herbal doctor email and I email him within 5 hr he respond to my email and I explain things to him he told me not to worry that I should fill his herbal form wish I did and he only request for little money that he will use to buy the items for the preparation of the herbal medicine, wish I send to him because the pain was too much for me to bear and after some days he told me that he has prepare the herbal medicine, that I should send him my address that he want to sent it to me via DHL or FED-EX that was how I got the herbal medication and I use it as I was told and after few days I found out that my herpes was no more and when some of my friend who has herpes saw me they were surprise and I also introduce them to the man and they are also cure from the same herpes and if you have herpes, kindly contact DR ODUCK AYAMUD via this email:oduckayamud49@yahoo.com OR oduckayamud49@gmail.com .... YOU CAN USE ANY OF THE EMAILS........ THIS MAN'S MEDICATION IS 100% EFFECTIVE AND ACTIVE .... CONTACT HIM TODAY VIA THIS EMAIL ADDRESS: oduckayamud49@yahoo.com OR oduckayamud49@gmail.com .... YOU CAN USE ANY OF THE EMAILS... so you can be happy again....YOU CAN ALSO ADD HIM UP ON WHATSAPP USING THIS MOBILE NUMBER:+2347059232579

    ReplyDelete
  10. I have been suffering from (HERPES) disease for the last four years and had constant pain, especially in my knees. During the first year, I had faith in God that I would be healed someday.This disease started to circulate all over my body and I have been taking treatment from my doctor, a few weeks ago I came on search on the internet if I could get any information concerning the prevention of this disease, on my search I saw a testimony of someone who has been healed from (Hepatitis B and Cancer) by this Man Dr. Silver and she also gave the email address of this man and advise we should contact him for any sickness that he would be of help, so I wrote to Dr. Silver telling him about my (HERPES Virus) he told me not to worry that I was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later I started experiencing changes all over me as the Dr. assured me that I have cured, after some time i went to my doctor to confirmed if I have been finally healed behold it was TRUE, So friends my advice is if you have such sickness or any other at all you can email Dr. Silver (drsilverhealingtemple@gmail.com) sir I am indeed grateful for the help I will forever recommend you to my friends!!! with your lovely Email Address ( drsilverhealingtemple@gmail.com

    ReplyDelete
  11. I’m here to testify about what Dr Okosun did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 4 years and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of Rose Smith on the internet testifying about a Man called Dr Okosun on how he cured her from 7 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,, Dr Okosun prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as Dr Okosun assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HBV, HIV, ALS, HBP, CANCER etc. you can contact Dr.Okosun for help via drokosun55@gmail or whatsapp +2348124363791 

    ReplyDelete
  12. I Want To Appreciate Dr.OYAGU for hs great deeds, I Was Diagnosed With type 2 Herpes Virus Last year,And Was Look For Solution To Be Cured Luckily I Saw Testimonies On How Dr.OYAGU Cure Herpes Virus I Decided To Contact Dr.OYAGU I Contacted Him He Prepared A Herbal Medicine Portion And Sent It To Me,I Started The Herbal Medicine For My Health.He Gave Me Step By Step Instructions On How To Apply It, When I Applied It As Instructed, I Was Cured Of This Deadly Herpes Within 2 weeks, I Am Now Herpes Negative.My Brother And Sister I No That There Are So Many People That Have There Same Herpes Virus Please contact Dr OYAGU To Help You Too,And Help Me To Thank Dr.OYAGU For Cure Me, I’m Cured By Dr. OYAGU Herbal Medicine,His Contact Email:oyaguspellcaster@gmail.com

    Or Cell Whatsapp Number +2348101755322 thank you .....

    ReplyDelete
  13. I’m here to testify about what Dr Okosun did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 4 years and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of Rose Smith on the internet testifying about a Man called Dr Okosun on how he cured her from 7 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,, Dr Okosun prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as Dr Okosun assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HBV, HIV, ALS, HBP, CANCER etc. you can contact Dr.Okosun for help via drokosun55@gmail or whatsapp +2348124363791

    ReplyDelete
  14. Hello, everyone! I,m here to explore blogs and forum about thonderful and most safe cure for (Herpes Virus).I was positive to the deadly virus called herpes and i lost hope because i was out casted and rejected even by my closet friends.i searched on-line to know and enquirer about cure for Herpes and i read someone testimony on how he was cured from Herpes so i decided to contact the same herbalist because i know that nature has the power to heal everything.i contacted him to know how he can help me and he told me never to worry that he will heal me with the natural herbs from God!after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via DHL and it got to me after 3 days!i used the med as he instructed me (MORNING and EVENING) and i was cured!its really like a dream but i am so happy!thats the reason i decided to also add more comment of Him so that more can be saved just like me!and if you need his help, you can email him on nativehealthclinic@gmail.com, or whatsapp +2348140073965 I,m neme amber and you can get in touch with me via nemeamber@gmail.com..Contact him for help at Herpes virus HIV/AIDS CANCER COPD BRAIN TUMOR All kind of virus and disease //..

    ReplyDelete
  15. Hello, everyone! I,m here to explore blogs and forum about thonderful and most safe cure for (Herpes Virus).I was positive to the deadly virus called herpes and i lost hope because i was out casted and rejected even by my closet friends.i searched on-line to know and enquirer about cure for Herpes and i read someone testimony on how he was cured from Herpes so i decided to contact the same herbalist because i know that nature has the power to heal everything.i contacted him to know how he can help me and he told me never to worry that he will heal me with the natural herbs from God!after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via DHL and it got to me after 3 days!i used the med as he instructed me (MORNING and EVENING) and i was cured!its really like a dream but i am so happy!thats the reason i decided to also add more comment of Him so that more can be saved just like me!and if you need his help, you can email him on nativehealthclinic@gmail.com, or whatsapp +2348140073965 I,m neme amber and you can get in touch with me via nemeamber@gmail.com..Contact him for help at Herpes virus HIV/AIDS CANCER COPD BRAIN TUMOR All kind of virus and disease //..

    ReplyDelete
  16. Hi everyone I'm Mrs Katrina Bennett, My husband divorced me 2 years ago to live with another woman and i have tried have him back but i could not, so i try to do many things to get him back and he refuse to come back. One faithful Friday morning, I visit a forum for tips on how to get your Ex back and there i saw a lady testifying on how Dr.alusi helped her to get her husband back after he was tie down with a spell by another woman. Although I never believed in spiritual work I reluctantly tried him because I was desperate and i contact him and explain my problems to him, to my greatest surprise Dr.alusi helped me to bring back my husband after 5days and now my relationship is more perfect just as he promised. Getting your ex back permanently does not only bring back someone you love but it will also reunite your lovers feelings. My husband now treats me like a Queen and always says he loves me all the time. If you are passing through difficulties in your relationship, Doctor alusi can help solve marital problems, restore broken relationships and some other things.I can assure he's highly potent and reliable. Email him for urgent help [dr.alusistanley@gmail.com] or +2348146050373.

    ReplyDelete
  17. Its a great pleasure for me to write this testimony about how i got my Genital Herpes cured a month ago. i have been reading so many comments of some people who were cured from various diseases by Dr Azaka but i never believed them. I was hurt and depressed so I was too curious and wanted to try Dr Azaka  herbal medicine, then i contacted him through his email, he assured me 100% that he will heal me, i pleaded with him to help me out. My experience with him was great, he healed me just as he promised. he sent me his medication which I took for a couple of days, and ask me to go for a medical check up after two weeks of usage. i agreed with him i took this medication and went for a check up, to my greatest surprise my result was negative, i am really happy that i am cured and healthy again. I have waited for 3weeks to be very sure i was completely healed before writing this testimony. I did another blood test one week ago and it was still Herpes negative. so i guess its time i recommend anyone going through the same way. reach him through his email address drazakaojezele@gmail com  or WhatsApp +2349059389105
    https://dr-azakaherbalremedy.webnode.com/products-

    ReplyDelete
  18. HOW I GOT RID OF MY HERPES Virus WITH THE HELP OF DR Aire. Greetings to the general public, i want to inform the general public how i was cured of HERPES Simplex Virus by a Doctor called Dr Aire. i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and is Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Doctor Dr Aire cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took as instructed and it seriously worked for me, i am a free person now without problem, my HERPES result came out negative. I pray for you Dr Aire God will give you everlasting life, you shall not die before your time for being a sincere and great man. Am so happy, you can also contact him if you have any problem like HIV/AID, CANCER,HERPATITIS,DIABETES,HPV,INFECTION ETC. Reach him on his Email Address at=== drairehome@gmail.com or you can contact him on WHATSAPP FOR EASY ACCESS at +2347036740271

    ReplyDelete
  19. Traditional Herbal doctor Sayo Cure HSV-2 Disease
    I want to thank Dr Sayo for helping me with his Herbal Medicine that cure my HSV-2 Disease completely.i have been living with HSV-2 Disease for the past 3yrs. i was so happy when i found DrSayo blogs: how Dr Sayo help people in the world.to cure HSV, with Herbal Medicine he Cured My HSV -2 Negative after using the Herbal Medicine Dr Sayo sent to me. I give thanks to God and healed completely. you are the best Traditional Herbal doctor in the world Dr Sayo, Contact Doctor Sayo Email sayoherbalhealer@gmail. com OR Contact Sayo by check FB Page https://www.facebook.com/Sayo-Herbal-Healer-100145798345000/  check website; http://sayoherbalhealer.website2.me/  check blog: https://sayoherbalhealer.blogspot.com/       

    ReplyDelete

  20. Its a miracle that I am alive today. I encounter HERPES SIMPLEX VIRUS (HSV1/2) for good four (4) years, six (6) months and twelve (12) day with my calculations, before I meet the great Dr. Abumere. I am Tina Richard from Fresno California, united state of America and I was affected with herpes virus.Herpes is a viral infection cause by the Herpes simplex virus, marked by painful, watery blister in the skin or mucous membrane or on the genitals. This was what I suffered for good four years. I have visited CVS Pharmacy in Fresno for treatment but no improvement. I meet Dr.Abumere online while I was searching for herpes cure I read a testimony about his work. I give a try that now becomes a testimony in my life. I contacted Dr.Abumere on Email: doctorabumere6@gmail.com or WhatsApp: +2349021975055

    ReplyDelete
  21. Am Richard, I am here to testify about a great herbalist  man who cured my wife of breast cancer. His name is Dr Imoloa. My wife went through this pain for 3 years, i almost spent all i had, until i saw some testimonies online on how Dr. Imoloa cure them from their diseases, immediately i contacted him through. then he told me the necessary things to do before he will send  the herbal medicine. Wish he did through DHL courier service, And he instructed us on how to apply or drink the medicine for good two weeks. and to greatest surprise before the upper third week my wife was relief from all the pains, Believe me, that was how my wife was cured from breast cancer by this great man. He also have powerful herbal medicine to cure diseases like: Alzheimer's disease, parkinson's disease, vaginal cancer, epilepsy Anxiety Disorders, Autoimmune Disease, Back Pain, Back Sprain, Bipolar Disorder, Brain Tumor, Malignant, Bruxism, Bulimia, Cervical Disc Disease, Cardiovascular Disease, Neoplasms , chronic respiratory disease, mental and behavioral disorder, Cystic Fibrosis, Hypertension, Diabetes, Asthma, Autoimmune inflammatory media arthritis ed. chronic kidney disease, inflammatory joint disease, impotence, alcohol spectrum feta, dysthymic disorder, eczema, tuberculosis, chronic fatigue syndrome, constipation, inflammatory bowel disease, lupus disease, mouth ulcer, mouth cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, HIV / AIDS, Huntington's disease, back acne, chronic kidney failure, addison's disease, chronic pain, Crohn's pain, cystic fibrosis, fibromyalgia, inflammatory Bowel disease, fungal nail disease, Lyme disease, Celia disease, Lymphoma, Major depression, Malignant melanoma, Mania, Melorheostosis, Meniere's disease, Mucopolysaccharidosis, Multiple sclerosis, Muscular dystrophy, Rheumatoid arthritis. You can reach him Email Via drimolaherbalmademedicine@gmail.com / whatsapp +2347081986098    Website/ www.drimolaherbalmademedicine.wordpress.com

    ReplyDelete
  22. I am happy to recommend dr Godday for his great help, i suffered for years seeking for the cure of herpes virus. i came across a testimony about his herbal medicine and i contacted him and he sent me a herbal remedy. I am happy to say that i am cured and negative of herpes virus type2. A doctor with many health experience and has many herbal medicine for most of the diseases you believed that had no cures. He has herbal remedies for Love spell,Cancer, Herpes virus, Lime, Hepatitis and Kidney disease Contact him on his Email: Goddayspiritualhome@gmail.com or Whats app only +1{919}4956404

    ReplyDelete
  23. When my herpes started interfering with my daily life. And my lips always bother me every damn day. I remember going to the hospital when I was around 25 years old cuz my whole lips were burning like hell. And a nurse came to the waiting lobby and said sorry there are no doctors here. So I had to go back home. My lips were burning like hell and I felt so uncomfortable that night so I turned to the internet where I found (multivitamin herbal cure cape town) . I am 40 years old.This virus has been totally eliminated with their herbal system , My lips were messed up. They are okay when I apply chapstick, but if I don’t apply chapstick they will get tight and dry and ashy and the skin will get burnt and hard. And they always feel tingly. The burning sensation stopped after that day I started their herbal cure.  I don’t want to walk around with glossy lips. I’m a man. I don’t know what would have heal me from this virus if not for the product. I took a comprehensive STD blood test last week again and everything came out negative.,contact > www.multivitamincare.org today Call Us (or SMS): +1 (956) 758-7882 they have the right treatment to STD.

    ReplyDelete
  24. I can't thank God enough for allowing me to meet dr ehiaguna. Any body reading this testimony now should help me to rejoice and thank dr ehiaguna for curing me completely from herpes virus . I was told i have herpes in 2015, i have been taking different kinds of medication still yet no improvement until i saw testimonies of a woman who dr ehiaguna helped to cure herpes. I was skeptical about contacting him but i also knew the importance of herbal medicine because i have heard about it before that he work perfectly, i made up my mind and contacted him we talked on phone and he prepared the herbs medicine and send the medicine  to me through DHL delivery services which i took according to his dosage information. Now I’m so happy I’m cured from Herpes my heart is so filled with joy because my herpes test came out negative, thank you so much Dr ehiaguna. If you are reading this and you have Herpes or any kind of disease whats-app him +2348073908953 or email him at, drehiaguna@gmail.com you can also visit his website   https://effectiveherbalcurehome.blogspot.com God bless you 

    ReplyDelete
  25. I can't thank God enough for allowing me to meet dr ehiaguna. Any body reading this testimony now should help me to rejoice and thank dr ehiaguna for curing me completely from herpes virus . I was told i have herpes in 2015, i have been taking different kinds of medication still yet no improvement until i saw testimonies of a woman who dr ehiaguna helped to cure herpes. I was skeptical about contacting him but i also knew the importance of herbal medicine because i have heard about it before that he work perfectly, i made up my mind and contacted him we talked on phone and he prepared the herbs medicine and send the medicine  to me through DHL delivery services which i took according to his dosage information. Now I’m so happy I’m cured from Herpes my heart is so filled with joy because my herpes test came out negative, thank you so much Dr ehiaguna. If you are reading this and you have Herpes or any kind of disease whats-app him +2348073908953 or email him at, drehiaguna@gmail.com you can also visit his website   https://effectiveherbalcurehome.blogspot.com God bless you 

    ReplyDelete
  26. few week ago I felt some pains and I went to the hospital my doc told me I had Herpes about 1 year ago and I need to start the treatment early, he gave me some medicine to be taking and I told him no I’ll not, because I hated taking medicine when I won’t not see cure for the purpose. After I got home I started getting worried searching for strong advice and I found valid natural treatment online a lot of people says they got herpes cure from DR.IMOUDU and I contacted DR.IMOUDU that same day I purchase his cure online, after two weeks of taking the herbel treatment i got cured totally. i tested negative all thank to DR.IMOUDU you can also reach him on his email: [DR.IMOUDUHEALERTEMPLE@GMAIL.COM ] or message him on WhatsApp +2348109609753 God bless you

    ReplyDelete
  27. few week ago I felt some pains and I went to the hospital my doc told me I had Herpes about 1 year ago and I need to start the treatment early, he gave me some medicine to be taking and I told him no I’ll not, because I hated taking medicine when I won’t not see cure for the purpose. After I got home I started getting worried searching for strong advice and I found valid natural treatment online a lot of people says they got herpes cure from DR.IMOUDU and I contacted DR.IMOUDU that same day I purchase his cure online, after two weeks of taking the herbel treatment i got cured totally. i tested negative all thank to DR.IMOUDU you can also reach him on his email: [DR.IMOUDUHEALERTEMPLE@GMAIL.COM ] or message him on WhatsApp +2348109609753 God bless you

    ReplyDelete
  28. Good luck to anyone reading this true life story of mine, I Was Diagnosed With type 1&2 Herpes Virus Last year, And I Was Looking For Solution To Be Cured Luckily I Saw Testimonies On How Dr Oso Cure Herpes Virus I Decided To Contact Dr Oso I Contacted Him He Prepared A Herbal Medicine Portion And Sent It To Me, I Started using the medication For My Health. He Gave Me Step By Step Instructions On How To Apply It, When I Applied It As Instructed, I Was Cured Of These Deadly Herpes Within 2 weeks, I Am Now Herpes Negative. My Brother And Sister I Know There Are So Many People That Have The Same Herpes Virus Please contact Dr Oso To Help You Too, And Help Me To Thank Dr Oso For Cure Me, I’m Cured By Dr. Oso Herbal Medicine, His Contact Email: drosohaberhome@gmail.com Or Cell WhatsApp Number +2348162084839 thank you

    Here is the DR website.....

    https://sites.google.com/view/drosohaberhome/

    you can also contact me for more info about Dr Oso maryjohnson9700@gmail.com

    ReplyDelete
  29. Getting rib of Herpes virus wasn't easy, I came across Dr voodoo on how he
    has cured so many people from herpes and other illness so I decided to give
    him a try, now am permanently cured using the natural herbs medication and
    cleansing supplement sent by Dr voodoo no more herpes, contact Dr voodoo
    WhatsApp number +2348140120719 also e-mail him at:
    voodoospelltemple66@gmail.com

    ReplyDelete
  30. I was cured___________Sure Treatment for herpes!!

    Please contact:

    Email R.buckler11 (((@gmail……com)))

    Thanks for reading!

    ReplyDelete

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